Blood Grouping Tests Held Not to Be Conclusive Evidence of Paternity
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ABO Blood Groups and Problems of Paternity (Symposium) Abstract of Introductory Words to the Symposium on Blood Groups in Paternity Cases
of Introductory Words to the Symposium on Blood Groups in Paternity Cases K. Henningsen Copenhagen, Denmark The ABO-groups are used for forensic purposes as disproof of alleged fatherhood since the middle of the twenties. For many years the reliability of this biological evidence has remained unchallenged the only pertinent exception to the laws of heredity formulated by Bernstein being the fam...
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BACKGROUND: The ABO blood groups result from DNA sequence variations, predominantly single nucleotide and insertion/deletion polymorphisms (SNPs and indels), in the ABO gene encoding a glycosyltransferase. The ABO blood groups A(1), A(2), B and O predominantly result from the wild type allele A1 and the major gene variants that are characterized by four diallelic markers (261G>del, 802G>A, 803G...
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Background & Aims: Mistyping either a donor or a recipient can lead to transfusion with ABO incompatible blood which results in severe intravascular hemolysis and may even result in the death of the recipient. ABO phenotype is one of the essential tests in immunohematology. Eighty percent of blood group A and AB persons are subtype A1 and A1B, respectively. The other 20% of these...
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